Combined polygenic risk scores, & predicting psychopathology
Description
In this podcast, we are joined by Dr. Alex Neumann, of the VIB Centre for Molecular Neurology at the University of Antwerp, and Professor Henning Tiemeier, Professor of Social and Behavioural Science at the Harvard T.H Chan School of Public Health in Boston and professor of psychiatric epidemiology at Erasmus University Medical Centre, Rotterdam. The focus is on their co-authored JCPP paper ‘Combined polygenic risk scores of different psychiatric traits predict general and specific psychopathology in childhood’.
Learning Objectives
1. Summary of the paper and highlighting the methodology used for the research, and some of the key findings.
2. How polygenic risk scores associated with school age psychopathology tended to either be associated with general psychopathology only or general and specific, but not except in the case of anxiety specific psychopathology only. Explanation of the importance of this finding and what it means for assessment and diagnosis. 3. Implications of their findings are for professionals working with young people and their families, what message they have to researchers in this field, and what they concluded in the paper.
Related Content Links
https://acamh.onlinelibrary.wiley.com/toc/14697610/2022/63/6