Polygenic scores for schizophrenia and major depression are associated with psychosocial risk factors in children

Duration: 5 mins

Description

Sandra Machlitt-Northen on her JCPP paper ‘Polygenic scores for schizophrenia and major depression are associated with psychosocial risk factors in children: evidence of gene–environment correlation’.

Learning Objectives

1. Investigate whether the genetic risk for schizophrenia (SCZ) and major depressive disorder (MDD) in children is correlated with established environmental and psychosocial risk factors.
2. Explore whether these associations vary between both psychopathologies.
3. Examine whether findings differ across two cohorts which were born 42 years apart.